Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 8/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.33 |
| ▸ | USP1 | O94782 | 2/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.31 |
| ▸ | EIF4E | P06730 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ICMT | O60725 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25554407 | 1.00 | NSD2 (0.37) | NSD2CYP11B2CYP19A1CYP11B1USP1 | |
| SCHEMBL25555246 | 0.93 | NSD2 (0.36) | NSD2CYP11B2CYP19A1CYP11B1PRKDC | |
| SCHEMBL23949272 | 0.92 | CYP19A1 (0.34) | NSD2CYP11B2CYP19A1CYP11B1USP1 | |
| SCHEMBL30353048 | 0.92 | CYP19A1 (0.34) | NSD2CYP11B2CYP19A1CYP11B1USP1 | |
| SCHEMBL30353064 | 0.88 | NSD2 (0.38) | NSD2CYP11B2CYP19A1CYP11B1USP1 | |
| SCHEMBL25554404 | 0.88 | NSD2 (0.38) | NSD2CYP11B2CYP19A1CYP11B1USP1 | |
| SCHEMBL23949240 | 0.88 | NSD2 (0.38) | NSD2CYP11B2CYP19A1CYP11B1PRKDC | |
| SCHEMBL25058663 | 0.87 | NSD2 (0.37) | NSD2CYP11B2CYP19A1CYP11B1PRKDC | |
| SCHEMBL30257183 | 0.87 | NSD2 (0.37) | NSD2CYP11B2CYP19A1CYP11B1PRKDC | |
| SCHEMBL30257092 | 0.86 | NSD2 (0.37) | NSD2CYP11B2CYP19A1CYP11B1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | claimed |
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |