Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | EIF4E | P06730 | 1/20 | 0.31 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.31 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23949271 | 0.77 | EIF4E (0.34) | EIF4EMKNK1MKNK2 | |
| SCHEMBL23949264 | 0.76 | — | — | |
| SCHEMBL23949239 | 0.76 | CYP19A1 (0.33) | EGLN2HTR2AKCNH2EIF4EMKNK1 | |
| SCHEMBL30353335 | 0.76 | CYP19A1 (0.33) | EGLN2HTR2AKCNH2EIF4EMKNK1 | |
| SCHEMBL23949599 | 0.75 | KMT2A (0.41) | — | |
| SCHEMBL23148790 | 0.63 | SLC22A12 (0.36) | — | |
| SCHEMBL25058663 | 0.62 | NSD2 (0.37) | EGLN2 | |
| SCHEMBL30257183 | 0.62 | NSD2 (0.37) | EGLN2 | |
| SCHEMBL23949600 | 0.61 | ADORA2A (0.45) | — | |
| SCHEMBL25555246 | 0.61 | NSD2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996910-A | Aryl or heteroaryl derivatives | 帝人制药株式会社 | 2023-04-21 | — | — | CN | disclosed |
| EP-4137481-A1 | ARYL OR HETEROARYL DERIVATIVE | Teijin Pharma Limited (JP) | 2023-02-22 | — | — | EP | disclosed |
| WO-2021210650-A1 | ARYL OR HETEROARYL DERIVATIVE | 帝人ファーマ株式会社 | 2021-10-21 | — | — | WO | disclosed |