SCHEMBL2395001

SCHEMBL2395001

C/N=C(/C(=O)NC)c1cc(Cl)cc(C)c1NC(=O)c1cc(Br)nn1-c1ncccc1Cl

nearest known ligand 0.80

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DHODH Q02127 3/20 0.41
▸ MALT1 Q9UDY8 4/20 0.34
▸ GRM4 Q14833 1/20 0.31
▸ TRPV1 Q8NER1 1/20 0.30
▸ PSD A5PKW4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2395002 1.00 DHODH (0.41) DHODHMALT1GRM4TRPV1PSD
SCHEMBL2396376 0.91 DHODH (0.43) DHODHMALT1TRPV1PSD
Chlorantraniliprole SCHEMBL29363261 0.89 DHODH (0.44) DHODHMALT1TRPV1PSD
Chlorantraniliprole SCHEMBL29551 0.89 DHODH (0.44) DHODHMALT1TRPV1PSD
SCHEMBL18795096 0.88 DHODH (0.43) DHODHMALT1GRM4TRPV1PSD
SCHEMBL29406173 0.88 DHODH (0.43) DHODHMALT1GRM4TRPV1PSD
SCHEMBL902720 0.87 DHODH (0.46) DHODHMALT1GRM4TRPV1PSD
SCHEMBL18400024 0.86 DHODH (0.43) DHODHMALT1TRPV1PSD
SCHEMBL12912066 0.86 DHODH (0.44) DHODHMALT1TRPV1PSD
SCHEMBL28836651 0.86 DHODH (0.45) DHODHMALT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8012499-B2 Anthranilamides for controlling invertebrate pests E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-06 — — US claimed
US-20090269300-A1 Anthranilamides for Controlling Invertebrate Pests FINKELSTEIN BRUCE LAWRENCE 2009-10-29 — — US claimed
US-8012499-B2 Anthranilamides for controlling invertebrate pests E.I. DU PONT DE NEMOURS AND COMPANY (US) 2011-09-06 — — US disclosed
US-20090269300-A1 Anthranilamides for Controlling Invertebrate Pests FINKELSTEIN BRUCE LAWRENCE 2009-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090269300-A1 Anthranilamides for Controlling Invertebrate Pests CYB5R3, CBR3, ANTXR2 DHODH 2158/4885MALT1 2601/4885GRM4 334/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback