Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 3/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.38 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23950576 | 0.86 | EPHB4 (0.41) | BRD4FGFR3SYKPIM1FLT3 | |
| SCHEMBL23390407 | 0.83 | PIM1 (0.42) | FGFR3KDRCNR1CNR2PIM1 | |
| SCHEMBL23925521 | 0.83 | AHR (0.38) | FGFR3KDRCNR1CNR2KDM5B | |
| SCHEMBL23390451 | 0.83 | AHR (0.42) | FGFR3KDRCNR1CNR2MAPK1 | |
| SCHEMBL23390448 | 0.83 | AHR (0.42) | FGFR3KDRCNR1CNR2MAPK1 | |
| SCHEMBL23390159 | 0.83 | FGFR3 (0.38) | FGFR3KDRCNR1CNR2SYK | |
| SCHEMBL25463600 | 0.83 | PIK3CA (0.41) | FGFR3KDRCNR1CNR2PIM1 | |
| SCHEMBL23390162 | 0.83 | FGFR3 (0.38) | FGFR3KDRCNR1CNR2SYK | |
| SCHEMBL23390288 | 0.83 | FGFR3 (0.38) | FGFR3KDRCNR1CNR2SYK | |
| SCHEMBL29738280 | 0.82 | AHR (0.41) | FGFR3KDRCNR1CNR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021210970-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AND THEIR USE AS ARYL HYDROCARBON RECEPTOR MODULATORS | DONG-A ST CO., LTD. (KR) | 2021-10-21 | — | — | WO | disclosed |