Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHB4 | P54760 | 1/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.40 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.39 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.39 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 8/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23416849 | 0.90 | FGFR2 (0.40) | EPHB4TEKBRD4NPBWR1FGFR2 | |
| SCHEMBL23950561 | 0.86 | BRD4 (0.43) | BRD4FGFR3SYKPIM1FLT3 | |
| SCHEMBL23950267 | 0.84 | TYK2 (0.39) | EPHB4TEKNPBWR1FGFR2FGFR3 | |
| SCHEMBL23951134 | 0.84 | EPHB4 (0.38) | EPHB4TEKNPBWR1FGFR2FGFR3 | |
| SCHEMBL23950919 | 0.84 | PIK3CA (0.39) | EPHB4TEKNPBWR1FGFR2FGFR3 | |
| SCHEMBL30101847 | 0.84 | PIK3CA (0.39) | EPHB4TEKNPBWR1FGFR2FGFR3 | |
| SCHEMBL23950694 | 0.84 | EPHB4 (0.38) | EPHB4TEKNPBWR1FGFR2FGFR3 | |
| SCHEMBL23950744 | 0.83 | KCNH2 (0.41) | EPHB4TEKNPBWR1FGFR2FGFR3 | |
| SCHEMBL23950750 | 0.83 | HSP90AA1 (0.38) | EPHB4TEKNPBWR1FGFR2FGFR3 | |
| SCHEMBL23925513 | 0.83 | TYK2 (0.40) | EPHB4TEKNPBWR1FGFR2FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021210970-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AND THEIR USE AS ARYL HYDROCARBON RECEPTOR MODULATORS | DONG-A ST CO., LTD. (KR) | 2021-10-21 | — | — | WO | disclosed |