Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TYK2 | P29597 | 2/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | JAK1 | P23458 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.36 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.35 |
| ▸ | TEK | Q02763 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MERTK | Q12866 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.34 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.34 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23925837 | 1.00 | KCNH2 (0.41) | KCNH2ALOX5CHRM1CYP2C9TYK2 | |
| SCHEMBL23950287 | 1.00 | KCNH2 (0.41) | KCNH2ALOX5CHRM1CYP2C9TYK2 | |
| SCHEMBL23950763 | 0.89 | KCNH2 (0.44) | KCNH2ALOX5CHRM1CYP2C9TYK2 | |
| SCHEMBL30101847 | 0.87 | PIK3CA (0.39) | FGFR2FGFR3EPHB4TEKAXL | |
| SCHEMBL23950919 | 0.87 | PIK3CA (0.39) | FGFR2FGFR3EPHB4TEKAXL | |
| SCHEMBL30101984 | 0.86 | EGFR (0.37) | KCNH2FGFR2FGFR3EPHB4TEK | |
| SCHEMBL23925838 | 0.86 | EGFR (0.37) | KCNH2FGFR2FGFR3EPHB4TEK | |
| SCHEMBL25463143 | 0.86 | PIK3CA (0.40) | TYK2FGFR2FGFR3EPHB4TEK | |
| SCHEMBL30102054 | 0.86 | PIK3CA (0.40) | TYK2FGFR2FGFR3EPHB4TEK | |
| SCHEMBL23950665 | 0.85 | KCNH2 (0.51) | KCNH2ALOX5CHRM1CYP2C9TRPV3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021210970-A1 | PYRIDOPYRIMIDINONE DERIVATIVES AND THEIR USE AS ARYL HYDROCARBON RECEPTOR MODULATORS | DONG-A ST CO., LTD. (KR) | 2021-10-21 | — | — | WO | disclosed |