Oxyphenisatine

Oxyphenisatine

SCHEMBL239513

O=C1Nc2ccccc2C1(c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 1.00
ADORA3 P0DMS8 1/20 1.00
KCNH2 Q12809 1/20 1.00
LMNA P02545 3/20 0.73
KMT2A Q03164 5/20 0.63
MAPT P10636 3/20 0.63
MEN1 O00255 3/20 0.63
XBP1 P17861 1/20 0.63
NPSR1 Q6W5P4 1/20 0.63
SMN1; SMN2 Q16637 2/20 0.61
GPR55 Q9Y2T6 3/20 0.58
CNR1 P21554 2/20 0.58
HTT P42858 1/20 0.58
GPR35 Q9HC97 1/20 0.58
MGAM O43451 3/20 0.47
GAA P10253 3/20 0.47
SI P14410 3/20 0.47
MGAM2 Q2M2H8 3/20 0.47
PDK2 Q15119 1/20 0.47
PDK4 Q16654 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyphenisatine SCHEMBL35387956 1.00 CHRM2 (1.00) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL2716060 0.97 CHRM2 (0.93) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL7031893 0.92 CHRM2 (0.85) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL13145364 0.92 CHRM2 (0.85) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL25502467 0.91 CHRM2 (0.82) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL13145367 0.89 CHRM2 (0.80) CHRM2ADORA3KCNH2LMNAKMT2A
Oxyphenisatine SCHEMBL11052368 0.89 CHRM2 (0.80) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL17814219 0.89 CHRM2 (0.80) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL3198592 0.88 CHRM2 (0.78) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL13145359 0.88 CHRM2 (0.78) CHRM2ADORA3KCNH2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2297 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4411282-B1 CRYOGENIC COOLING SYSTEM OXFORD NANOSCIENCE LTD (GB) 2026-04-01 EP claimed
EP-4447755-B1 BABY ROCKER AND KIT COMPRISING SUCH A BABY ROCKER POYET MOTTE PUERICULTURE (FR) 2026-02-04 EP claimed
EP-3946793-B1 MANUFACTURING METHOD OF SURFACE EXCHANGER STRUCTURE FOR AIRCRAFT NACELLE SAFRAN NACELLES (FR) 2026-01-14 EP claimed
EP-4627237-A1 MULTI-WAY VALVE VALEO SYSTEMES THERMIQUES (FR) 2025-10-08 EP claimed
EP-4057648-B1 SPEECH COMMUNICATION METHOD AND SYSTEM UNDER BROADBAND AND NARROW-BAND INTERCOMMUNICATION ENVIRONMENT HYTERA COMM CORP LTD (CN) 2025-07-02 EP claimed
US-20250138026-A1 METHOD FOR DIAGNOSING COLLAGEN DEGRADATION ASSOCIATED DISEASE HOSPICES CIVILS DE LYON (FR) 2025-05-01 US claimed
EP-4525870-A1 METHODS OF TREATING CUSHING'S SYNDROME AND LIVER DISORDERS, AND OF REDUCING LIVER TOXICITY OF OTHER DRUGS ADMINISTERED TO A PATIENT Corcept Therapeutics Incorporated (US) 2025-03-26 EP claimed
EP-4316211-B1 LIGHTING DEVICE FOR A MOTOR VEHICLE HEADLIGHT CAPABLE OF DETECTING SHORT CIRCUITS ZKW GROUP GMBH (AT) 2025-02-26 EP claimed
EP-4473010-A1 METHOD FOR DIAGNOSING COLLAGEN DEGRADATATION ASSOCIATED DISEASE Institut National de la Santé et de la Recherche Médicale (INSERM) (FR) 2024-12-11 EP claimed
EP-4470620-A2 OXYPHENISATIN ACETATE, OXYPHENISATIN AND BISACODYL FOR TREATING TRIPLE-NEGATIVE BREAST CANCER The United States of America, as represented by the Secretary, Department of Health and Human Services (US) 2024-12-04 EP claimed
EP-1569795-A1 THERMOPLASTIC ARTICLE HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2005-09-07 EP claimed
CN-1640262-A Cockroach gel bait SONGDELONG SCIENCE TECHNOLOGY (CN) 2005-07-20 CN claimed
US-6896966-B2 Articles of manufacture incorporating polyester/polycarbonate blends EASTMAN CHEMICAL COMPANY (US) 2005-05-24 US claimed
WO-2004048089-A1 ARTICLES OF MANUFACTURE INCORPORATING POLYESTER/POLYCARBONATE BLENDS EASTMAN CHEMICAL COMPANY (US) 2004-06-10 WO claimed
WO-2004048090-A1 THERMOPLASTIC ARTICLE HAVING A DECORATIVE MATERIAL EMBEDDED THEREIN EASTMAN CHEMICAL COMPANY (US) 2004-06-10 WO claimed
US-20040101678-A1 Thermoplastic article having a decorative material embedded therein EASTMAN CHEMICAL COMPANY 2004-05-27 US claimed
US-20040101687-A1 Articles of manufacture incorporating polyester/polycarbonate blends EASTMAN CHEMICAL COMPANY 2004-05-27 US claimed
EP-0938338-A1 CARRIER COMPOSITION FOR INFLUENCING THE TIGHT JUNCTION PERMEABILITY Ghyssaert, Joris Rosa Michael (BE) 1999-09-01 EP claimed
WO-1998005359-A1 CARRIER COMPOSITION FOR INFLUENCING THE TIGHT JUNCTION PERMEABILITY GHYSSAERT, JORIS, ROSA, MICHAEL (BE) 1998-02-12 WO claimed
EP-0821970-A1 Carrier composition for influencing the tight junction permeability Verhaeren, Edward Henri Charles (BE) 1998-02-04 EP claimed