SCHEMBL17814219

SCHEMBL17814219

O=Nc1ccc(C2(c3ccc(O)cc3)C(=O)Nc3ccccc32)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.80
ADORA3 P0DMS8 1/20 0.80
KCNH2 Q12809 1/20 0.80
LMNA P02545 3/20 0.59
KMT2A Q03164 5/20 0.53
MAPT P10636 3/20 0.53
MEN1 O00255 3/20 0.53
XBP1 P17861 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
SMN1; SMN2 Q16637 2/20 0.52
GPR55 Q9Y2T6 3/20 0.49
CNR1 P21554 2/20 0.49
HTT P42858 1/20 0.49
GPR35 Q9HC97 1/20 0.49
GAA P10253 4/20 0.40
MGAM O43451 3/20 0.40
SI P14410 3/20 0.40
MGAM2 Q2M2H8 3/20 0.40
PDK2 Q15119 1/20 0.39
PDK4 Q16654 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17813124 0.93 LMNA (0.69) CHRM2ADORA3KCNH2LMNAKMT2A
Oxyphenisatine SCHEMBL35387956 0.89 CHRM2 (1.00) CHRM2ADORA3KCNH2LMNAKMT2A
Oxyphenisatine SCHEMBL239513 0.89 CHRM2 (1.00) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL2716060 0.86 CHRM2 (0.93) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL17813127 0.86 LMNA (0.59) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL13145364 0.82 CHRM2 (0.85) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL7031893 0.82 CHRM2 (0.85) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL25502467 0.81 CHRM2 (0.82) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL13145369 0.81 CHRM2 (0.76) CHRM2ADORA3KCNH2LMNAKMT2A
SCHEMBL13145367 0.80 CHRM2 (0.80) CHRM2ADORA3KCNH2LMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016087480-A1 COPOLYCARBONATE COMPOSITIONS WITH IMPROVED PROCESSING BEHAVIOUR CONTAINING PE-WAX COVESTRO DEUTSCHLAND AG (DE) 2016-06-09 WO disclosed