SCHEMBL23955957

SCHEMBL23955957

CC(=O)C1=CC=CCC1C(C)=O

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13569156 0.79 HSD17B10 (0.34)
SCHEMBL12393666 0.78 CHRNB2 (0.34) CHRNB2CHRNA7CHRNA4
SCHEMBL18843499 0.78 CHRNB2 (0.34) CHRNB2CHRNA7CHRNA4
SCHEMBL13369570 0.76 CHRNB2 (0.33) CHRNB2CHRNA7CHRNA4
SCHEMBL14492505 0.76
SCHEMBL19390140 0.76 CHRNB2 (0.33) CHRNB2CHRNA7CHRNA4
SCHEMBL18951843 0.76
SCHEMBL13459899 0.76 CA1 (0.31)
SCHEMBL1354859 0.69 ABAT (0.31)
SCHEMBL24405813 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2596805-B1 Prodrug comprising a drug-linker conjugate ASCENDIS PHARMA AS (DK) 2021-10-27 EP disclosed