Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23956570 | 0.86 | POLB (0.40) | POLBNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL23956596 | 0.85 | POLB (0.39) | POLBNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL23956582 | 0.83 | LMNA (0.30) | LMNAHTT | |
| SCHEMBL20636697 | 0.82 | POLB (0.42) | POLBNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL19993455 | 0.81 | POLB (0.40) | POLBNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL23956606 | 0.79 | POLB (0.39) | POLBNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL23956663 | 0.77 | POLB (0.40) | POLBNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL10281057 | 0.77 | POLB (0.41) | POLBNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL18866473 | 0.77 | POLB (0.41) | POLBNPC1RAB9AMEN1ALDH1A1 | |
| SCHEMBL15412515 | 0.76 | POLB (0.41) | POLBNPC1RAB9AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515921-B1 | PYRAZOLO[1,5-A]PYRIDINE DERIVATIVES AND THEIR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-10-27 | — | — | EP | disclosed |