Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | RXRB | P28702 | 3/20 | 0.39 |
| ▸ | RXRG | P48443 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.38 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.38 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21584456 | 1.00 | MEN1 (0.42) | MEN1KMT2AHIF1ARXRARXRB | |
| SCHEMBL30257817 | 1.00 | MEN1 (0.42) | MEN1KMT2AHIF1ARXRARXRB | |
| SCHEMBL30257818 | 1.00 | MEN1 (0.42) | MEN1KMT2AHIF1ARXRARXRB | |
| SCHEMBL9057677 | 0.93 | MEN1 (0.48) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL24621932 | 0.93 | SIRT1 (0.42) | MEN1KMT2AHIF1ARXRARXRB | |
| SCHEMBL23635989 | 0.93 | MRGPRX4 (0.40) | MEN1KMT2AHIF1ARXRARXRB | |
| SCHEMBL23630711 | 0.93 | HIF1A (0.44) | MEN1KMT2AHIF1AHPGDNR4A2 | |
| SCHEMBL29706710 | 0.92 | HIF1A (0.39) | MEN1KMT2AHIF1ARXRARXRB | |
| SCHEMBL23630721 | 0.91 | HIF1A (0.44) | MEN1KMT2AHIF1ANR4A2 | |
| SCHEMBL23630731 | 0.89 | HIF1A (0.41) | HIF1ARXRARXRBRXRGHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-10-24 | — | — | US | disclosed |
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2022-07-14 | — | — | US | disclosed |
| WO-2021213500-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (CN) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220218730-A1 | COMPOUNDS AND PHARMACEUTICAL USES THEREOF | HRH4, OR10J3, CYP3A5 | MEN1 527/4885KMT2A 4419/4885HIF1A 3197/4885 |
| US-11793823-B2 | Compounds and pharmaceutical uses thereof | HRH4, OR10J3, CYP3A5 | MEN1 527/4885KMT2A 4419/4885HIF1A 3197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.