Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | COMT | P21964 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.34 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | UQCRB | P14927 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23957954 | 0.88 | NPC1 (0.37) | NPC1HSP90AA1L3MBTL1COMTCYP1A2 | |
| SCHEMBL19869615 | 0.83 | BRD4 (0.46) | NPC1HSP90AA1L3MBTL1COMTBRD4 | |
| SCHEMBL18232751 | 0.78 | HTR3A (0.34) | NPC1HSP90AA1L3MBTL1CYP1A2CYP3A4 | |
| SCHEMBL23957953 | 0.77 | BRD4 (0.37) | L3MBTL1BRD4KDM4E | |
| SCHEMBL19869614 | 0.74 | BRD4 (0.50) | NPC1HSP90AA1L3MBTL1BRD4FEN1 | |
| SCHEMBL14336996 | 0.71 | HSP90AA1 (0.48) | NPC1HSP90AA1L3MBTL1COMTCYP3A4 | |
| SCHEMBL23957951 | 0.71 | BRD4 (0.35) | BRD4FEN1KAT2B | |
| SCHEMBL23957955 | 0.71 | KDM5A (0.34) | BRD4FEN1KAT2BPARP1 | |
| SCHEMBL21931157 | 0.70 | MAPT (0.44) | HSP90AA1L3MBTL1COMTCYP1A2CYP3A4 | |
| SCHEMBL14867109 | 0.70 | ACVR1 (0.35) | NPC1COMTCYP1A2CYP3A4GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210330646-A1 | FASCIN BINDING COMPOUNDS FOR SPINOGENESIS | SPINOGENIX, INC. | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210330646-A1 | FASCIN BINDING COMPOUNDS FOR SPINOGENESIS | FSCN1, SMN1; SMN2, DCX | NPC1 4121/4885HSP90AA1 2095/4885L3MBTL1 722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.