Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.76 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.76 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.64 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12769542 | 1.00 | HTT (0.76) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL16621782 | 1.00 | HTT (0.76) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL17247214 | 1.00 | HTT (0.76) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL822844 | 1.00 | HTT (0.76) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL12268296 | 0.94 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL822843 | 0.94 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL4569586 | 0.94 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL10084171 | 0.94 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL2606163 | 0.94 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA | |
| SCHEMBL822947 | 0.94 | HTT (0.85) | HTTSMN1; SMN2TDP1L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217175-A1 | IONOMERS WITH MACROCYCLIC MOIETIES FOR ION CONDUCTIVITY AND PERMSELECTIVITY | NUTECH VENTURES (US) | 2021-10-28 | — | — | WO | disclosed |