SCHEMBL2395842

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12236734	0.88	NR3C1 (0.43)	NR3C1MAPTPGRNR3C2AR
	SCHEMBL2394611	0.87	MAPT (0.41)	NR3C1MAPTHTTPGRLMNA
	SCHEMBL2396042	0.86	NR3C1 (0.47)	NR3C1PGRNR3C2AR
	SCHEMBL2347682	0.86	MAPT (0.45)	NR3C1MAPTHTTPGRLMNA
	SCHEMBL2393891	0.84	MAPT (0.43)	NR3C1MAPTHTTPGRLMNA
	SCHEMBL2397705	0.84	NR3C1 (0.45)	NR3C1MAPTPGRNR3C2AR
	SCHEMBL5032285	0.83	NR3C1 (0.43)	NR3C1PGRNR3C2AR
	SCHEMBL1780349	0.83	MAPT (0.47)	NR3C1MAPTHTTPGRLMNA
	SCHEMBL448833	0.83	NR3C1 (0.48)	NR3C1PGRNR3C2AR
	SCHEMBL461978	0.82	NR3C1 (0.42)	NR3C1MAPTPGRNR3C2AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.