Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958602 | 0.85 | CNR2 (0.42) | KDM4EALDH1A1CNR2KMT2AMEN1 | |
| SCHEMBL2114318 | 0.76 | KMT2A (0.61) | KDM4EALDH1A1CNR2KMT2AMEN1 | |
| SCHEMBL23905572 | 0.76 | KDM4E (0.47) | KDM4EALDH1A1CNR2KMT2AMEN1 | |
| SCHEMBL23046588 | 0.74 | CA12 (0.49) | KDM4EALDH1A1CA12CA1CA2 | |
| SCHEMBL25113893 | 0.74 | ALDH1A1 (0.49) | KDM4EALDH1A1CNR2KMT2AMEN1 | |
| SCHEMBL16544886 | 0.74 | MAPT (0.43) | KDM4EALDH1A1CNR2KMT2AMEN1 | |
| SCHEMBL21729783 | 0.72 | KDM4E (0.55) | KDM4EALDH1A1CNR2KMT2AMEN1 | |
| SCHEMBL18969524 | 0.72 | KMT2A (0.51) | KDM4EALDH1A1CNR2KMT2AMEN1 | |
| SCHEMBL23883075 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1CNR2KMT2AMAPT | |
| SCHEMBL23930090 | 0.72 | KDM4E (0.46) | KDM4EALDH1A1CNR2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |