Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 6/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958763 | 1.00 | CFTR (0.40) | CFTRALDH1A1L3MBTL1CNR2CNR1 | |
| SCHEMBL23958714 | 0.93 | CFTR (0.40) | CFTRALDH1A1L3MBTL1CNR2CNR1 | |
| SCHEMBL23958876 | 0.92 | CFTR (0.33) | CFTRAAK1 | |
| SCHEMBL23958688 | 0.91 | CFTR (0.32) | CFTRCNR1AAK1 | |
| SCHEMBL23958681 | 0.91 | CFTR (0.32) | CFTRCNR1AAK1 | |
| SCHEMBL23958867 | 0.91 | CFTR (0.32) | CFTR | |
| SCHEMBL23958682 | 0.91 | XDH (0.34) | CFTRALDH1A1KDM4EHPGDAAK1 | |
| SCHEMBL23958593 | 0.88 | CFTR (0.39) | CFTRCNR2CNR1ADORA2AADORA1 | |
| SCHEMBL26926330 | 0.85 | CFTR (0.39) | CFTRALDH1A1L3MBTL1CNR2CNR1 | |
| SCHEMBL23958855 | 0.83 | CFTR (0.38) | CFTRALDH1A1L3MBTL1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |