Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958593 | 0.86 | CFTR (0.39) | CFTRCNR2CNR1ADORA2AADORA1 | |
| SCHEMBL23930254 | 0.79 | CFTR (0.33) | CFTRCNR2CNR1MAPK14SLC34A1 | |
| SCHEMBL25686491 | 0.78 | CFTR (0.36) | CFTRCNR2CNR1ADORA2AADORA1 | |
| SCHEMBL23930276 | 0.78 | CFTR (0.36) | CFTRCNR2CNR1ADORA2AADORA1 | |
| SCHEMBL23958821 | 0.78 | CFTR (0.36) | CFTRCNR2CNR1ADORA2AADORA1 | |
| SCHEMBL30007319 | 0.78 | ADORA2A (0.40) | CFTRCNR2CNR1MAPK14ADORA2A | |
| SCHEMBL23930153 | 0.78 | ADORA2A (0.40) | CFTRCNR2CNR1MAPK14ADORA2A | |
| SCHEMBL23958855 | 0.76 | CFTR (0.38) | CFTRCNR2CNR1TNIKMAPK14 | |
| SCHEMBL26926330 | 0.76 | CFTR (0.39) | CFTRCNR2CNR1 | |
| SCHEMBL23958591 | 0.75 | CFTR (0.38) | CFTRCNR2CNR1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |