Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | TNKS | O95271 | 1/20 | 0.30 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.30 |
| ▸ | DHODH | Q02127 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958642 | 0.79 | CFTR (0.38) | CFTRCNR1CNR2MAPK14SLC34A1 | |
| SCHEMBL23930153 | 0.78 | ADORA2A (0.40) | CFTRCNR1CNR2MAPK14SLC34A1 | |
| SCHEMBL30007319 | 0.78 | ADORA2A (0.40) | CFTRCNR1CNR2MAPK14SLC34A1 | |
| SCHEMBL23958593 | 0.77 | CFTR (0.39) | CFTRCNR1CNR2SLC34A1 | |
| SCHEMBL30007930 | 0.75 | CFTR (0.35) | CFTRCNR1CNR2MAPK14SLC34A1 | |
| SCHEMBL23958680 | 0.75 | CFTR (0.35) | CFTRCNR1CNR2MAPK14SLC34A1 | |
| SCHEMBL23958839 | 0.71 | CFTR (0.39) | CFTRCNR1CNR2MAPK14SLC34A1 | |
| SCHEMBL23930276 | 0.71 | CFTR (0.36) | CFTRCNR1CNR2SLC34A1CYP11B1 | |
| SCHEMBL23958821 | 0.71 | CFTR (0.36) | CFTRCNR1CNR2SLC34A1CYP11B1 | |
| SCHEMBL25686491 | 0.71 | CFTR (0.36) | CFTRCNR1CNR2SLC34A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139293-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-03-01 | — | — | EP | disclosed |
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |