Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25689048 | 0.85 | CFTR (0.37) | ALDH1A1L3MBTL1KDM4EHPGDNPC1 | |
| SCHEMBL23958693 | 0.81 | CFTR (0.40) | ALDH1A1L3MBTL1GABRA2GABRB2MAPK14 | |
| SCHEMBL25686910 | 0.80 | CFTR (0.35) | ALDH1A1L3MBTL1MAPK14LMNACFTR | |
| SCHEMBL26727261 | 0.79 | CFTR (0.34) | MAPK14CFTR | |
| SCHEMBL23958619 | 0.77 | CFTR (0.41) | ALDH1A1L3MBTL1KDM4EHPGDNPC1 | |
| SCHEMBL30007475 | 0.77 | CFTR (0.41) | ALDH1A1L3MBTL1KDM4EHPGDNPC1 | |
| SCHEMBL23930265 | 0.73 | ADORA2A (0.40) | ALDH1A1L3MBTL1PKMMAPK14CFTR | |
| SCHEMBL28909138 | 0.73 | CFTR (0.34) | ALDH1A1L3MBTL1LMNACFTR | |
| SCHEMBL30692527 | 0.73 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1MAPK14LMNACFTR | |
| SCHEMBL26926417 | 0.73 | ALDH1A1 (0.35) | ALDH1A1L3MBTL1MAPK14LMNACFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023237732-A1 | RSV INHIBITING TRIAZOLO BEARING DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-12-14 | — | — | WO | disclosed |
| US-20230203004-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| WO-2023052593-A1 | RSV INHIBITING SPIRO BEARING DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-04-06 | — | — | WO | disclosed |
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203004-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | ACE2, SIRT7, ACE | ALDH1A1 1630/4885L3MBTL1 4845/4885PTGS2 2304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.