Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.37 |
| ▸ | CNR2 | P34972 | 4/20 | 0.34 |
| ▸ | CNR1 | P21554 | 3/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 5/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28909204 | 0.85 | CFTR (0.41) | CFTRDHODH | |
| SCHEMBL23958821 | 0.82 | CFTR (0.36) | CFTRCNR2CNR1SLC34A1 | |
| SCHEMBL25686491 | 0.82 | CFTR (0.36) | CFTRCNR2CNR1SLC34A1 | |
| SCHEMBL23930276 | 0.82 | CFTR (0.36) | CFTRCNR2CNR1SLC34A1 | |
| SCHEMBL23958684 | 0.81 | CFTR (0.41) | CFTRCNR2CNR1MAPTFPR2 | |
| SCHEMBL25279639 | 0.76 | CFTR (0.43) | CFTRCNR2CNR1ALDH1A1MAPT | |
| SCHEMBL23958587 | 0.75 | CFTR (0.34) | CFTRCNR2CNR1 | |
| SCHEMBL23930153 | 0.74 | ADORA2A (0.40) | CFTRCNR2CNR1SLC34A1 | |
| SCHEMBL30007319 | 0.74 | ADORA2A (0.40) | CFTRCNR2CNR1SLC34A1 | |
| SCHEMBL23958938 | 0.74 | CFTR (0.38) | CFTRCNR2CNR1SLC34A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |