Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | ABL1 | P00519 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958739 | 0.82 | TRPV3 (0.34) | CFTR | |
| SCHEMBL23958793 | 0.78 | CFTR (0.35) | CFTRCNR1CNR2 | |
| SCHEMBL23958820 | 0.75 | CFTR (0.37) | CFTRCNR1CNR2 | |
| SCHEMBL23958756 | 0.74 | SLC34A1 (0.33) | — | |
| SCHEMBL23958627 | 0.74 | CFTR (0.36) | CFTRCNR1CNR2 | |
| SCHEMBL23958642 | 0.72 | CFTR (0.38) | CFTRCNR1CNR2 | |
| SCHEMBL23958593 | 0.70 | CFTR (0.39) | CFTRCNR1CNR2 | |
| SCHEMBL23930254 | 0.70 | CFTR (0.33) | CFTRCNR1CNR2 | |
| SCHEMBL23930153 | 0.69 | ADORA2A (0.40) | CFTRCNR1CNR2 | |
| SCHEMBL30007319 | 0.69 | ADORA2A (0.40) | CFTRCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |