Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25285247 | 0.82 | CFTR (0.34) | CFTRPDE4B | |
| SCHEMBL25687380 | 0.82 | CFTR (0.34) | CFTRPDE4B | |
| SCHEMBL30006761 | 0.82 | CFTR (0.34) | CFTRPDE4B | |
| SCHEMBL23958813 | 0.80 | CFTR (0.32) | CFTR | |
| SCHEMBL23958982 | 0.80 | CFTR (0.33) | CFTR | |
| SCHEMBL26769106 | 0.78 | CFTR (0.33) | CFTRKLKB1 | |
| SCHEMBL30007745 | 0.76 | CFTR (0.34) | CFTR | |
| SCHEMBL25686209 | 0.76 | CFTR (0.34) | CFTR | |
| SCHEMBL30007232 | 0.76 | CFTR (0.34) | CFTRPDE4B | |
| SCHEMBL26766255 | 0.76 | CFTR (0.34) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |