Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687300 | 1.00 | CFTR (0.34) | CFTRLMNATP53RIPK1KCNH2 | |
| SCHEMBL30007164 | 0.94 | P2RX7 (0.33) | CFTRLMNATP53RIPK1KCNH2 | |
| SCHEMBL25687297 | 0.94 | P2RX7 (0.33) | CFTRLMNATP53RIPK1KCNH2 | |
| SCHEMBL25687225 | 0.91 | CFTR (0.35) | CFTRRIPK1CTSAALDH1A1CNR1 | |
| SCHEMBL25687503 | 0.90 | CFTR (0.38) | CFTRRIPK1PDE4B | |
| SCHEMBL30007052 | 0.90 | CFTR (0.34) | CFTRRIPK1SMN1; SMN2CNR1HTR2C | |
| SCHEMBL25687509 | 0.90 | CFTR (0.34) | CFTRRIPK1SMN1; SMN2CNR1HTR2C | |
| SCHEMBL25285098 | 0.89 | LMNA (0.32) | CFTRLMNATP53RIPK1KCNH2 | |
| SCHEMBL30007745 | 0.88 | CFTR (0.34) | CFTRLMNATP53RIPK1KCNH2 | |
| SCHEMBL25686209 | 0.88 | CFTR (0.34) | CFTRLMNATP53RIPK1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |