Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958839 | 0.86 | CFTR (0.39) | CFTRSMN1; SMN2 | |
| SCHEMBL23958600 | 0.81 | CFTR (0.36) | CFTRSMN1; SMN2 | |
| SCHEMBL23958693 | 0.76 | CFTR (0.40) | CFTR | |
| SCHEMBL30007930 | 0.73 | CFTR (0.35) | CFTRSMN1; SMN2 | |
| SCHEMBL23958680 | 0.73 | CFTR (0.35) | CFTRSMN1; SMN2 | |
| SCHEMBL25686612 | 0.72 | CFTR (0.40) | CFTRSMN1; SMN2 | |
| SCHEMBL25686626 | 0.71 | CFTR (0.37) | CFTRSMN1; SMN2 | |
| SCHEMBL30006751 | 0.71 | CYP11B1 (0.34) | CFTR | |
| SCHEMBL23958746 | 0.71 | CYP11B1 (0.34) | CFTR | |
| SCHEMBL30211307 | 0.69 | HTR2A (0.34) | CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |