Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.34 |
| ▸ | SLC34A1 | Q06495 | 3/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958680 | 1.00 | CFTR (0.35) | CFTRCNR2CNR1SLC34A1CYP11B1 | |
| SCHEMBL23958839 | 0.87 | CFTR (0.39) | CFTRCNR2CNR1SLC34A1CYP11B1 | |
| SCHEMBL30006751 | 0.86 | CYP11B1 (0.34) | CFTRCNR2CNR1SLC34A1CYP11B1 | |
| SCHEMBL23958746 | 0.86 | CYP11B1 (0.34) | CFTRCNR2CNR1SLC34A1CYP11B1 | |
| SCHEMBL23930153 | 0.82 | ADORA2A (0.40) | CFTRCNR2CNR1SLC34A1CYP11B1 | |
| SCHEMBL30007319 | 0.82 | ADORA2A (0.40) | CFTRCNR2CNR1SLC34A1CYP11B1 | |
| SCHEMBL28909155 | 0.79 | CFTR (0.33) | CFTRCNR2CNR1SLC34A1CYP11B1 | |
| SCHEMBL25778781 | 0.75 | CFTR (0.38) | CFTRADORA2AADORA1SMN1; SMN2MAPK14 | |
| SCHEMBL25689498 | 0.75 | CFTR (0.38) | CFTRADORA3ADORA2ASMN1; SMN2MAPK14 | |
| SCHEMBL23930254 | 0.75 | CFTR (0.33) | CFTRCNR2CNR1SLC34A1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |