Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958613 | 0.69 | CA12 (0.43) | ALDH1A1HPGDHTTKMT2A | |
| SCHEMBL2989542 | 0.65 | KDM4E (0.52) | ALDH1A1HPGDHTTMEN1CYP3A4 | |
| SCHEMBL28757019 | 0.63 | CYP3A4 (0.48) | ALDH1A1HPGDHTTMEN1CYP3A4 | |
| SCHEMBL2902942 | 0.62 | HSP90AB1 (0.42) | ALDH1A1HPGDHTTMEN1CYP3A4 | |
| SCHEMBL17826360 | 0.62 | PPARA (0.44) | ALDH1A1MEN1CYP3A4PTGS1DRD3 | |
| SCHEMBL11382828 | 0.62 | MAPT (0.50) | ALDH1A1HPGDHTTMEN1CYP3A4 | |
| SCHEMBL7343180 | 0.61 | HPGD (0.49) | ALDH1A1HPGDHTTMEN1CYP3A4 | |
| SCHEMBL13785011 | 0.61 | SMN1; SMN2 (0.42) | ALDH1A1HPGDHTTMEN1CYP3A4 | |
| SCHEMBL13974085 | 0.60 | PPARA (0.45) | ALDH1A1CYP3A4HSD11B1 | |
| SCHEMBL8892922 | 0.60 | KDM4E (0.43) | ALDH1A1HPGDHTTMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |