Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PDE6D | O43924 | 1/20 | 0.45 |
| ▸ | PDE6A | P16499 | 1/20 | 0.45 |
| ▸ | PDE6G | P18545 | 1/20 | 0.45 |
| ▸ | PDE6B | P35913 | 1/20 | 0.45 |
| ▸ | PDE6C | P51160 | 1/20 | 0.45 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.43 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958784 | 0.85 | PDE4A (0.39) | KMT2AMEN1RXFP1SMPD1NPC1 | |
| SCHEMBL23958791 | 0.84 | KMT2A (0.52) | KMT2AMEN1RXFP1SMPD1NPC1 | |
| SCHEMBL23905404 | 0.80 | ATM (0.47) | KMT2AMEN1NPC1POLBL3MBTL1 | |
| SCHEMBL23195851 | 0.79 | CNR2 (0.49) | POLBL3MBTL1HPGDS | |
| SCHEMBL30007092 | 0.78 | PARP1 (0.48) | NPC1KDM4EALDH1A1HPGDSRAB9A | |
| SCHEMBL23905400 | 0.77 | HSD17B2 (0.49) | KMT2AMEN1NPC1HPGDSRAB9A | |
| SCHEMBL9902404 | 0.74 | KMT2A (0.63) | KMT2AMEN1RXFP1SMPD1NPC1 | |
| SCHEMBL23196217 | 0.72 | ATM (0.44) | KMT2AMEN1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL23904743 | 0.72 | CCR1 (0.52) | RXFP1KDM4EALDH1A1HPGDSMAPT | |
| SCHEMBL30692522 | 0.72 | CCR1 (0.42) | NPC1POLBKDM4ERAB9AFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |