Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | PDE6D | O43924 | 1/20 | 0.38 |
| ▸ | PDE6A | P16499 | 1/20 | 0.38 |
| ▸ | PDE6G | P18545 | 1/20 | 0.38 |
| ▸ | PDE6B | P35913 | 1/20 | 0.38 |
| ▸ | PDE6C | P51160 | 1/20 | 0.38 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23958866 | 0.85 | KMT2A (0.51) | MEN1KMT2ARXFP1PDE6DPDE6A | |
| SCHEMBL25687961 | 0.82 | ATM (0.41) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30007139 | 0.81 | KMO (0.40) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL23196004 | 0.81 | KMO (0.40) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL23905483 | 0.81 | CA12 (0.39) | PDE4BPDE4DKMT2ALMNANPC1 | |
| SCHEMBL30211305 | 0.80 | PARP1 (0.43) | PDE4APDE4BPDE4CPDE4DLMNA | |
| SCHEMBL23905586 | 0.76 | HPGDS (0.47) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23958594 | 0.75 | CCR1 (0.44) | — | |
| SCHEMBL23905722 | 0.74 | HPGDS (0.45) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL23905484 | 0.71 | CCR1 (0.40) | RXFP1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |