Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 16/20 | 0.39 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25697148 | 0.87 | ACSS2 (0.33) | PTGFRACSS2KDM4EALDH1A1 | |
| SCHEMBL23958806 | 0.83 | CFTR (0.34) | PTGFRACSS2KDM4EALDH1A1LMNA | |
| SCHEMBL23958726 | 0.78 | CFTR (0.35) | PTGFRACSS2KDM4EALDH1A1LMNA | |
| SCHEMBL25687479 | 0.77 | CFTR (0.40) | PTGFR | |
| SCHEMBL25686197 | 0.77 | CFTR (0.40) | PTGFR | |
| SCHEMBL25687478 | 0.77 | CFTR (0.40) | PTGFR | |
| SCHEMBL23958886 | 0.77 | CFTR (0.40) | PTGFR | |
| SCHEMBL25687518 | 0.77 | CFTR (0.40) | PTGFR | |
| SCHEMBL30211296 | 0.77 | CFTR (0.40) | PTGFR | |
| SCHEMBL25697304 | 0.76 | ACSS2 (0.32) | PTGFRACSS2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |