Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 4/20 | 0.35 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | ULK1 | O75385 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25281599 | 1.00 | CFTR (0.35) | CFTRSSTR5KCNH2GABRA5AR | |
| SCHEMBL25687266 | 0.94 | CFTR (0.34) | CFTRSSTR5KCNH2GABRA5AR | |
| SCHEMBL25280037 | 0.94 | CFTR (0.34) | CFTRSSTR5KCNH2GABRA5AR | |
| SCHEMBL25687485 | 0.91 | CFTR (0.36) | CFTRGABRA5ARULK1LMNA | |
| SCHEMBL25687495 | 0.91 | CFTR (0.39) | CFTRGABRA5ULK1RIPK1 | |
| SCHEMBL25232424 | 0.90 | CFTR (0.33) | CFTRSSTR5KCNH2GABRA5AR | |
| SCHEMBL30006951 | 0.90 | CFTR (0.33) | CFTRSSTR5KCNH2GABRA5AR | |
| SCHEMBL25687289 | 0.90 | CFTR (0.33) | CFTRSSTR5KCNH2GABRA5AR | |
| SCHEMBL23959003 | 0.89 | AR (0.38) | CFTRSSTR5KCNH2ARMCHR1 | |
| SCHEMBL25687527 | 0.89 | AR (0.38) | CFTRSSTR5KCNH2ARMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203004-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | JANSSEN PHARMACEUTICA NV (BE) | 2023-06-29 | — | — | US | disclosed |
| WO-2021214136-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2021-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230203004-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | ACE2, SIRT7, ACE | CFTR 508/4885SSTR5 2828/4885KCNH2 3238/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.