Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 3/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | SSTR5 | P35346 | 3/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HPGDS | O60760 | 1/20 | 0.31 |
| ▸ | ULK1 | O75385 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25687289 | 1.00 | CFTR (0.33) | CFTRARSSTR5KCNH2GABRA5 | |
| SCHEMBL25232424 | 1.00 | CFTR (0.33) | CFTRARSSTR5KCNH2GABRA5 | |
| SCHEMBL25687285 | 0.94 | CNR1 (0.34) | CFTRARSSTR5KCNH2GABRA5 | |
| SCHEMBL25687293 | 0.94 | POLB (0.34) | SSTR5KCNH2CNR1MCHR1ENPP2 | |
| SCHEMBL30006884 | 0.94 | CNR1 (0.34) | CFTRARSSTR5KCNH2GABRA5 | |
| SCHEMBL23958649 | 0.94 | POLB (0.34) | SSTR5KCNH2CNR1MCHR1ENPP2 | |
| SCHEMBL30007202 | 0.94 | POLB (0.34) | SSTR5KCNH2CNR1MCHR1ENPP2 | |
| SCHEMBL23958645 | 0.93 | GABRA5 (0.36) | ARGABRA5CNR1ENPP2CYP2C9 | |
| SCHEMBL30007230 | 0.93 | GABRA5 (0.36) | ARGABRA5CNR1ENPP2CYP2C9 | |
| SCHEMBL25686195 | 0.93 | GABRA5 (0.36) | ARGABRA5CNR1ENPP2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4139293-A1 | RSV INHIBITING 3-SUBSTITUTED QUINOLINE AND CINNOLINE DERIVATIVES | Janssen Sciences Ireland Unlimited Company (IE) | 2023-03-01 | — | — | EP | disclosed |
| CN-115461336-A | RSV inhibiting 3-substituted quinoline and cinnoline derivatives | 爱尔兰詹森科学公司 | 2022-12-09 | — | — | CN | disclosed |