Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959064 | 0.91 | BCHE (0.44) | BCHEGAACDK1GPR119LMNA | |
| SCHEMBL23959123 | 0.89 | BCHE (0.43) | BCHEGAATSHRCDK1GPR119 | |
| SCHEMBL23959036 | 0.89 | BCHE (0.49) | BCHEGAATSHRCDK1GPR119 | |
| SCHEMBL23959076 | 0.88 | BCHE (0.40) | BCHEGAATSHRCDK1TP53 | |
| SCHEMBL23959057 | 0.88 | CDK1 (0.46) | BCHEGAATSHRCDK1CYP2C19 | |
| SCHEMBL23959005 | 0.88 | BCHE (0.40) | BCHEGAATSHRCDK1MAPT | |
| SCHEMBL23959420 | 0.88 | BCHE (0.40) | BCHEGAATSHRCDK1TP53 | |
| SCHEMBL31499314 | 0.88 | BCHE (0.41) | BCHEGAATSHRCDK1GPR119 | |
| SCHEMBL23959142 | 0.87 | ALDH1A1 (0.42) | BCHEGAATSHRCDK1CYP1A2 | |
| SCHEMBL23958997 | 0.81 | BCHE (0.40) | BCHEGAATSHRCDK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021212974-A1 | RACEMIC AND CHIRAL 3-(2,3-BUTADIENYL)OXYINDOLINONE COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 复旦大学 (CN) | 2021-10-28 | — | — | WO | disclosed |