Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 5/20 | 0.69 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.69 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.69 |
| ▸ | NCOR2 | Q9Y618 | 5/20 | 0.69 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.64 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.64 |
| ▸ | STAT3 | P40763 | 1/20 | 0.63 |
| ▸ | MIF | P14174 | 4/20 | 0.60 |
| ▸ | PDE6D | O43924 | 4/20 | 0.60 |
| ▸ | BCL2 | P10415 | 3/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959186 | 1.00 | HDAC3 (0.69) | HDAC3HDAC1HDAC2NCOR2DDB1 | |
| SCHEMBL24474235 | 0.99 | HDAC3 (0.69) | HDAC3HDAC1HDAC2NCOR2DDB1 | |
| Formic Acid SCHEMBL29794414 | 0.97 | HDAC3 (0.65) | HDAC3HDAC1HDAC2NCOR2DDB1 | |
| SCHEMBL23959145 | 0.96 | HDAC3 (0.68) | HDAC3HDAC1HDAC2NCOR2DDB1 | |
| Formic Acid SCHEMBL29794485 | 0.96 | HDAC3 (0.65) | HDAC3HDAC1HDAC2NCOR2DDB1 | |
| Formic Acid SCHEMBL29794445 | 0.93 | HDAC3 (0.65) | HDAC3HDAC1HDAC2NCOR2DDB1 | |
| SCHEMBL24474131 | 0.91 | HDAC3 (0.67) | HDAC3HDAC1HDAC2NCOR2DDB1 | |
| SCHEMBL24474218 | 0.91 | HDAC3 (0.67) | HDAC3HDAC1HDAC2NCOR2DDB1 | |
| SCHEMBL24474291 | 0.91 | HDAC3 (0.67) | HDAC3HDAC1HDAC2NCOR2DDB1 | |
| SCHEMBL29794429 | 0.91 | CRBN (0.63) | HDAC3HDAC1HDAC2NCOR2DDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216828-A1 | CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-10-28 | — | — | WO | disclosed |