Sugi Predict

Sugi Predict / Compounds / Formic Acid

Formic Acid

Formic Acid

SCHEMBL29794445

CNC(=O)CCCNc1cccc2c1C(=O)N(C1CCC(=O)NC1=O)C2=O.O=CO

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HDAC3 O15379 4/20 0.65
▸ HDAC1 Q13547 4/20 0.65
▸ HDAC2 Q92769 4/20 0.65
▸ NCOR2 Q9Y618 4/20 0.65
▸ CRBN Q96SW2 7/20 0.62
▸ DDB1 Q16531 5/20 0.62
▸ STAT3 P40763 2/20 0.57
▸ MIF P14174 1/20 0.56
▸ PDE6D O43924 6/20 0.56
▸ CA2 P00918 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formic Acid SCHEMBL29794485 0.97 HDAC3 (0.65) HDAC3HDAC1HDAC2NCOR2CRBN
Formic Acid SCHEMBL29794414 0.97 HDAC3 (0.65) HDAC3HDAC1HDAC2NCOR2CRBN
SCHEMBL23959145 0.96 HDAC3 (0.68) HDAC3HDAC1HDAC2NCOR2CRBN
Formic Acid SCHEMBL29794437 0.95 CRBN (0.64) HDAC3HDAC1HDAC2NCOR2CRBN
SCHEMBL24474235 0.94 HDAC3 (0.69) HDAC3HDAC1HDAC2NCOR2CRBN
SCHEMBL23959186 0.93 HDAC3 (0.69) HDAC3HDAC1HDAC2NCOR2CRBN
SCHEMBL23959052 0.93 HDAC3 (0.69) HDAC3HDAC1HDAC2NCOR2CRBN
Formic Acid SCHEMBL29794430 0.93 HDAC1 (0.67) HDAC3HDAC1HDAC2NCOR2CRBN
SCHEMBL29794429 0.89 CRBN (0.63) HDAC3HDAC1HDAC2NCOR2CRBN
SCHEMBL29794459 0.89 CRBN (0.65) HDAC3HDAC1HDAC2NCOR2CRBN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115043817-A SOS1 proteolysis regulator and preparation method and application thereof 苏州泽璟生物制药股份有限公司 2022-09-13 — — CN disclosed