Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 15/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 7/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.39 |
| ▸ | FAP | Q12884 | 7/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PREP | P48147 | 4/20 | 0.37 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22794202 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL12747459 | 0.86 | DPP4 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL20707055 | 0.83 | DPP4 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL15765626 | 0.83 | DPP4 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL19457587 | 0.82 | DPP4 (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL10080104 | 0.81 | DPP4 (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL12747472 | 0.81 | HPGD (0.44) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL12402520 | 0.81 | NR1I2 (0.40) | — | |
| SCHEMBL12293760 | 0.81 | NR1I2 (0.40) | — | |
| SCHEMBL23959050 | 0.81 | DPP4 (0.37) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192534-A1 | CYCLIN-DEPENDENT KINASE 9 (CDK9) DEGRADERS AND METHODS OF USING THEREOF | OHIO STATE INNOVATION FOUNDATION (US) | 2023-10-05 | — | — | WO | disclosed |
| WO-2021216828-A1 | CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-10-28 | — | — | WO | disclosed |