Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.37 |
| ▸ | FAP | Q12884 | 4/20 | 0.37 |
| ▸ | STAT6 | P42226 | 2/20 | 0.36 |
| ▸ | ACE | P12821 | 4/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.35 |
| ▸ | PREP | P48147 | 2/20 | 0.35 |
| ▸ | PITRM1 | Q5JRX3 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PEPD | P12955 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25757942 | 0.87 | DPP4 (0.39) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL22525831 | 0.87 | DPP4 (0.39) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8088388 | 0.86 | DPP4 (0.40) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL21696763 | 0.84 | STAT6 (0.43) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL25885362 | 0.84 | STAT6 (0.43) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL26749977 | 0.83 | DPP4 (0.35) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL26749959 | 0.82 | STAT6 (0.38) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL26751293 | 0.82 | STAT6 (0.36) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL25024047 | 0.82 | ACE (0.41) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8243995 | 0.82 | STAT6 (0.39) | DPP4DPP8DPP9STAT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216828-A1 | CHIMERIC DEGRADERS OF CYCLIN-DEPENDENT KINASE 9 AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-10-28 | — | — | WO | disclosed |