Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 10/20 | 0.51 |
| ▸ | AKT2 | P31751 | 10/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PAK4 | O96013 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | GRK5 | P34947 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959251 | 0.87 | AKT1 (0.58) | AKT1AKT2ROCK2PIM1GSK3B | |
| SCHEMBL23959310 | 0.82 | AKT1 (0.56) | AKT1AKT2ROCK2PIM1GSK3B | |
| SCHEMBL23959235 | 0.82 | AKT1 (0.53) | AKT1AKT2ROCK2PIM1GSK3B | |
| SCHEMBL23959234 | 0.80 | AKT1 (0.54) | AKT1AKT2ROCK2PIM1GSK3B | |
| SCHEMBL23959250 | 0.78 | AKT1 (0.53) | AKT1AKT2ROCK2PIM1GSK3B | |
| SCHEMBL22484956 | 0.77 | PDE6D (0.38) | MEN1HPGDKMT2AL3MBTL1 | |
| SCHEMBL23959205 | 0.76 | AKT1 (0.47) | AKT1AKT2ROCK2PIM1GSK3B | |
| SCHEMBL22522876 | 0.75 | L3MBTL1 (0.37) | MEN1USP2HPGDMAPK1KMT2A | |
| SCHEMBL23959207 | 0.73 | AKT1 (0.56) | AKT1AKT2ROCK2PIM1GSK3B | |
| SCHEMBL22871622 | 0.73 | L3MBTL1 (0.35) | MEN1HPGDKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192901-B2 | Nitrogen-containing heterocyclic organic compound and organic electroluminescent device | SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2021-12-07 | — | — | US | disclosed |
| US-20210332066-A1 | NITROGEN-CONTAINING HETEROCYCLIC ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | SHENZHEN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11192901-B2 | Nitrogen-containing heterocyclic organic compound and organic electroluminescent device | H1-10, H1-0, OR10J3 | AKT1 1176/4885AKT2 1711/4885ROCK2 2074/4885 |
| US-20210332066-A1 | NITROGEN-CONTAINING HETEROCYCLIC ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE | H1-10, H1-0, OR10J3 | AKT1 1176/4885AKT2 1711/4885ROCK2 2074/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.