Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 19/20 | 0.51 |
| ▸ | CNR2 | P34972 | 13/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2395936 | 1.00 | CNR1 (0.51) | CNR1CNR2MKNK1 | |
| SCHEMBL2396140 | 0.88 | CNR1 (0.52) | CNR1CNR2MKNK1 | |
| SCHEMBL2396149 | 0.88 | CNR1 (0.52) | CNR1CNR2MKNK1 | |
| SCHEMBL2394832 | 0.88 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL2394834 | 0.88 | CNR1 (0.53) | CNR1CNR2 | |
| SCHEMBL2396199 | 0.86 | CNR1 (0.50) | CNR1CNR2MKNK1 | |
| SCHEMBL2396202 | 0.86 | CNR1 (0.50) | CNR1CNR2MKNK1 | |
| SCHEMBL2390971 | 0.85 | CNR1 (0.73) | CNR1CNR2 | |
| SCHEMBL12266148 | 0.85 | CNR1 (0.73) | CNR1CNR2 | |
| SCHEMBL2390972 | 0.85 | CNR1 (0.73) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8012957-B2 | Tetrahydro-1H-1,2,6-triaza-azulene cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2011-09-06 | — | — | US | claimed |
| US-20070259853-A1 | TETRAHYDRO-1H-1,2,6-TRIAZA-AZULENE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-08 | — | — | US | claimed |
| US-8012957-B2 | Tetrahydro-1H-1,2,6-triaza-azulene cannabinoid modulators | JANSSEN PHARMACEUTICA NV (BE) | 2011-09-06 | — | — | US | disclosed |
| US-20070259853-A1 | TETRAHYDRO-1H-1,2,6-TRIAZA-AZULENE CANNABINOID MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259853-A1 | TETRAHYDRO-1H-1,2,6-TRIAZA-AZULENE CANNABINOID MODULATORS | CNR1, CNR2, GPR18 | CNR1 1/4885CNR2 2/4885MKNK1 1478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.