Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS11D | O60235 | 1/20 | 0.49 |
| ▸ | CTRL | P40313 | 1/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 8/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.49 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.49 |
| ▸ | CYP3A43 | Q9HB55 | 2/20 | 0.49 |
| ▸ | PSMB9 | P28065 | 2/20 | 0.49 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.49 |
| ▸ | PSMB10 | P40306 | 2/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.49 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.49 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.49 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.49 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23959820 | 0.92 | TMPRSS11D (0.51) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL23959804 | 0.86 | PSMB5 (0.68) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL2605636 | 0.83 | BIRC2 (0.55) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL25515843 | 0.83 | PSMB5 (0.62) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL85103 | 0.81 | ALDH1A1 (0.58) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL19474595 | 0.80 | BIRC2 (0.54) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL84540 | 0.80 | BIRC2 (0.54) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL13893311 | 0.80 | BIRC2 (0.54) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL85133 | 0.80 | PSMB5 (0.68) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 | |
| SCHEMBL23959808 | 0.80 | PSMB5 (0.64) | TMPRSS11DCTRLPSMB5CYP3A4CYP3A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216670-A1 | INHIBITORS OF HUMAN EPIDIDYMUS PROTEIN 4 | UNIVERSITY OF ROCHESTER (US) | 2021-10-28 | — | — | WO | disclosed |