Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIPC | P11150 | 1/20 | 0.35 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13162853 | 0.78 | KMT2A (0.36) | LIPCLIPGKMT2A | |
| SCHEMBL13561507 | 0.78 | KMT2A (0.36) | LIPCLIPGKMT2A | |
| SCHEMBL18912346 | 0.78 | KMT2A (0.36) | LIPCLIPGKMT2A | |
| SCHEMBL13654490 | 0.78 | — | — | |
| SCHEMBL26385627 | 0.74 | — | — | |
| SCHEMBL26385628 | 0.74 | — | — | |
| SCHEMBL3056172 | 0.74 | — | — | |
| SCHEMBL21468985 | 0.74 | LIPC (0.41) | LIPCLIPGKMT2A | |
| SCHEMBL24214240 | 0.74 | HRH3 (0.35) | LIPCLIPGKMT2A | |
| SCHEMBL791729 | 0.74 | NPC1 (0.41) | KMT2APIK3CAMTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214117-A1 | HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2021-10-28 | — | — | WO | disclosed |