Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.30 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23960376 | 0.86 | TDP1 (0.31) | TDP1 | |
| SCHEMBL24153348 | 0.81 | TDP1 (0.38) | TDP1 | |
| SCHEMBL25943312 | 0.80 | — | — | |
| SCHEMBL24153423 | 0.74 | TDP1 (0.38) | TDP1 | |
| SCHEMBL24153955 | 0.73 | TDP1 (0.37) | TDP1 | |
| SCHEMBL10153053 | 0.72 | CASP1 (0.31) | TDP1 | |
| SCHEMBL14471826 | 0.71 | FCER2 (0.32) | — | |
| SCHEMBL24220954 | 0.71 | CYP2D6 (0.40) | TDP1 | |
| SCHEMBL25942372 | 0.70 | TDP1 (0.32) | TDP1 | |
| SCHEMBL12088988 | 0.70 | FCER2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021217019-A1 | RAS INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-10-28 | — | — | WO | disclosed |