Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 1.00 |
| ▸ | LTA4H | P09960 | 9/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18579795 | 0.76 | EPHX2 (0.73) | EPHX2LTA4HHPGDHTTSMN1; SMN2 | |
| SCHEMBL1905934 | 0.76 | LTA4H (0.62) | EPHX2LTA4HCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL28529055 | 0.75 | LTA4H (0.69) | EPHX2LTA4HCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20481432 | 0.74 | EPHX2 (0.69) | EPHX2LTA4HLMNAKCNH2 | |
| SCHEMBL1903396 | 0.73 | LTA4H (0.60) | EPHX2LTA4HPTGS1PTGS2CYP1A2 | |
| SCHEMBL20481361 | 0.73 | EPHX2 (0.69) | EPHX2LTA4HLMNA | |
| SCHEMBL1903808 | 0.72 | CYP1A2 (0.64) | EPHX2LTA4HCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20481523 | 0.72 | EPHX2 (0.68) | EPHX2LTA4HALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL23111500 | 0.72 | LTA4H (0.65) | EPHX2LTA4HCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL20481349 | 0.72 | EPHX2 (0.67) | EPHX2LTA4HLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021214048-A1 | DUAL INHIBITORS OF SOLUBLE EPOXIDE HYDROLASE AND 5-LIPOXYGENASE | Johann Wolfgang Goethe-Universität Frankfurt am Main (DE) | 2021-10-28 | — | — | WO | disclosed |