SCHEMBL23960768

SCHEMBL23960768

CC(C)c1ccc(C(C)(C)N=O)nc1OCC1CC1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 20/20 0.39
CNR1 P21554 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25510495 0.85 CNR2 (0.38) CNR2CNR1
SCHEMBL25510494 0.84 CNR2 (0.39) CNR2CNR1
SCHEMBL25510523 0.83 CNR2 (0.39) CNR2CNR1
SCHEMBL23960763 0.80 CNR2 (0.37) CNR2CNR1
SCHEMBL25511041 0.77 TRPV1 (0.45) CNR2CNR1
SCHEMBL25511040 0.77 TRPV1 (0.45) CNR2CNR1
SCHEMBL23960764 0.76 CNR2 (0.39) CNR2CNR1
SCHEMBL25510508 0.76 DHFR (0.39) CNR2CNR1
SCHEMBL25510499 0.73 CNR2 (0.40) CNR2CNR1
SCHEMBL25510497 0.72 CNR2 (0.39) CNR2CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021215656-A1 BENZIMIDAZOLONE-BASED CINNAMAMIDE DERIVATIVE AS TRPV1 ANTAGONIST AND PHARMACEUTICAL COMPOSITION FOR TREATMENT OR PREVENTION OF PAIN CONTAINING SAME AS ACTIVE INGREDIENT 주식회사 제이맥켐 (KR) 2021-10-28 WO disclosed