Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 13/20 | 0.61 |
| ▸ | THRB | P10828 | 13/20 | 0.61 |
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.61 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.61 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.61 |
| ▸ | ASPH | Q12797 | 1/20 | 0.61 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.61 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.61 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23960909 | 0.90 | EGLN1 (0.57) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL23961052 | 0.85 | EGLN1 (0.59) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL30397088 | 0.85 | EGLN1 (0.49) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL28554576 | 0.84 | EGLN1 (0.48) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL30751026 | 0.84 | THRA (0.84) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL14672081 | 0.84 | THRA (0.84) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL524684 | 0.80 | THRA (0.60) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL522601 | 0.79 | THRA (0.60) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL523084 | 0.79 | THRA (0.74) | THRATHRBEGLN1BBOX1SLC6A2 | |
| SCHEMBL522168 | 0.77 | THRA (0.71) | THRATHRBEGLN1BBOX1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115867537-A | Improved process for the preparation of a rasagiline base | 迈兰实验室有限公司 | 2023-03-28 | — | — | CN | disclosed |
| WO-2021214785-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ROXADUSTAT | MYLAN LABORATORIES LIMITED (IN) | 2021-10-28 | — | — | WO | disclosed |