Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23462594 | 0.81 | CHRNA7 (0.35) | PDE4BPDE4DCHRNA7PIK3CD | |
| SCHEMBL24245195 | 0.80 | LMNA (0.30) | — | |
| SCHEMBL16889120 | 0.69 | — | — | |
| SCHEMBL2284513 | 0.69 | — | — | |
| SCHEMBL4454355 | 0.69 | — | — | |
| SCHEMBL16885275 | 0.69 | PIK3CD (0.33) | PDE4BPDE4DCHRNA7PIK3CD | |
| SCHEMBL21136842 | 0.69 | CHRNA7 (0.31) | PDE4BPDE4DCHRNA7 | |
| SCHEMBL17037488 | 0.69 | PIK3CD (0.33) | PDE4BPDE4DCHRNA7PIK3CD | |
| SCHEMBL16885277 | 0.69 | PIK3CD (0.33) | PDE4BPDE4DCHRNA7PIK3CD | |
| SCHEMBL20355342 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216656-A1 | 5-MEMBERED HETEROARYL CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES, INC. (US) | 2021-10-28 | — | — | WO | disclosed |
| WO-2021216642-A1 | PYRAZOLE CARBOXAMIDE COMPOUNDS FOR TREATMENT OF HBV | ASSEMBLY BIOSCIENCES, INC. (US) | 2021-10-28 | — | — | WO | disclosed |