Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.47 |
| ▸ | DRD3 | P35462 | 9/20 | 0.47 |
| ▸ | DRD4 | P21917 | 8/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25202850 | 0.88 | PDGFRB (0.47) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL23964250 | 0.83 | DRD2 (0.53) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL23964181 | 0.82 | HRH3 (0.53) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL23964260 | 0.80 | DRD4 (0.54) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL30042174 | 0.79 | DRD2 (0.51) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL23932585 | 0.79 | DRD2 (0.51) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL23964261 | 0.78 | DRD4 (0.64) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL23964265 | 0.78 | DRD4 (0.54) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL23964237 | 0.78 | DRD2 (0.54) | DRD2DRD3DRD4HTR1AADRA2A | |
| SCHEMBL30041683 | 0.78 | DRD4 (0.54) | DRD2DRD3DRD4HTR1AADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216665-A9 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-12-02 | — | — | WO | disclosed |
| WO-2021216665-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-10-28 | — | — | WO | disclosed |