Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 8/20 | 0.38 |
| ▸ | DRD3 | P35462 | 8/20 | 0.38 |
| ▸ | HTR2A | P28223 | 7/20 | 0.38 |
| ▸ | CCR8 | P51685 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23964310 | 0.83 | HRH4 (0.55) | HRH4DRD2DRD3HTR2ACCR8 | |
| SCHEMBL30297589 | 0.83 | HRH4 (0.55) | HRH4DRD2DRD3HTR2ACCR8 | |
| SCHEMBL23964193 | 0.75 | HRH4 (0.55) | HRH4DRD2DRD3CCR8HTR1A | |
| SCHEMBL23964309 | 0.71 | HRH4 (0.57) | HRH4DRD2DRD3CCR8HTR2C | |
| SCHEMBL30041280 | 0.71 | HRH4 (0.57) | HRH4DRD2DRD3CCR8HTR2C | |
| SCHEMBL23964194 | 0.69 | DRD4 (0.43) | HRH4DRD2DRD3CCR8HTR1A | |
| SCHEMBL25505716 | 0.67 | HRH4 (0.52) | HRH4DRD2DRD3HTR1AADRA2A | |
| SCHEMBL30040884 | 0.67 | HRH4 (0.52) | HRH4DRD2DRD3HTR1AADRA2A | |
| SCHEMBL6782457 | 0.67 | HRH4 (0.63) | HRH4DRD2DRD3HTR2AHTR2C | |
| SCHEMBL6782266 | 0.65 | HRH4 (0.56) | HRH4DRD2DRD3HTR2AHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021216665-A9 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-12-02 | — | — | WO | disclosed |
| WO-2021216665-A1 | COLLAGEN 1 TRANSLATION INHIBITORS AND METHODS OF USE THEREOF | ANIMA BIOTECH INC. (US) | 2021-10-28 | — | — | WO | disclosed |