Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | MGLL | Q99685 | 6/20 | 0.39 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | CTRC | Q99895 | 1/20 | 0.32 |
| ▸ | TRIP13 | Q15645 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23974181 | 0.80 | GAA (0.47) | GAAMGLLFAAHNR1H3 | |
| SCHEMBL18211463 | 0.79 | MGLL (0.62) | GAAMGLLFAAHRAB9AALDH1A1 | |
| SCHEMBL9492443 | 0.78 | MGLL (0.59) | GAAESR1MGLLFAAHELANE | |
| SCHEMBL13820062 | 0.76 | MGLL (0.65) | GAAMGLLTHRBFAAHNR1H3 | |
| SCHEMBL18211377 | 0.75 | GAA (0.54) | GAAALDH1A1KDM4ECYP2C19LMNA | |
| SCHEMBL30110715 | 0.75 | GAA (0.54) | GAAMGLLFAAHNR1H3TDP1 | |
| SCHEMBL22440450 | 0.74 | GAA (0.48) | GAAMGLLFAAHALDH1A1 | |
| SCHEMBL6685103 | 0.72 | ESR1 (0.74) | ESR1THRATHRBHSD11B1ALDH1A1 | |
| SCHEMBL12631701 | 0.71 | ELANE (0.62) | GAAMGLLELANEF2CTSG | |
| SCHEMBL14199135 | 0.71 | GAA (0.60) | GAAMGLLTHRBFAAHELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210330798-A1 | TREATMENT OF INFECTIONS | ASCENDIS PHARMA A/S (DK) | 2021-10-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210330798-A1 | TREATMENT OF INFECTIONS | H1-10, PM20D2, ELANE | GAA 854/4885ESR1 3312/4885MGLL 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.