Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | HNF4A | P41235 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23986574 | 0.94 | IDO1 (0.49) | IDO1ALOX5ALDH1A1RECQLESR1 | |
| SCHEMBL30536496 | 0.94 | ASIC3 (0.44) | IDO1ASIC3ALOX5ALDH1A1RECQL | |
| SCHEMBL21858952 | 0.94 | ASIC3 (0.44) | IDO1ASIC3ALOX5ALDH1A1RECQL | |
| SCHEMBL30536490 | 0.94 | ASIC3 (0.44) | IDO1ASIC3ALOX5ALDH1A1RECQL | |
| SCHEMBL30536495 | 0.87 | IDO1 (0.44) | IDO1ASIC3ALOX5ALDH1A1RECQL | |
| SCHEMBL21858514 | 0.87 | IDO1 (0.44) | IDO1ASIC3ALOX5ALDH1A1RECQL | |
| SCHEMBL30536494 | 0.87 | IDO1 (0.44) | IDO1ASIC3ALOX5ALDH1A1RECQL | |
| SCHEMBL23986705 | 0.85 | FFAR1 (0.39) | IDO1ASIC3ALDH1A1RECQLGRM5 | |
| SCHEMBL23986581 | 0.85 | CYP1A1 (0.46) | IDO1ASIC3ALOX5ALDH1A1RECQL | |
| SCHEMBL21950437 | 0.84 | ASIC3 (0.37) | IDO1ASIC3ALDH1A1RECQLCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-11-18 | — | — | US | disclosed |
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | REUTER CHEMISCHE APPARATEBAU E.K. (DE) | 2021-11-04 | — | — | US | disclosed |
| EP-3904442-A1 | RESIN COMPOSITION, MOLDED BODY, OPTICAL LENS, AND OPTICAL LENS UNIT | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210340317-A1 | POLYCYCLIC COMPOUNDS | CBR1, C1R, CBR3 | IDO1 2883/4885ASIC3 1634/4885ALOX5 196/4885 |
| US-20210355058-A1 | POLYCYCLIC COMPOUNDS | CBR1, CBR3, C1R | IDO1 3072/4885ASIC3 1443/4885ALOX5 176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.