Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23969482 | 0.91 | CYP3A4 (0.34) | ESR1ESR2CYP3A4CYP2D6KMT2A | |
| SCHEMBL23967844 | 0.81 | CXCR5 (0.32) | CYP3A4GAACXCR5KDM4EHPGD | |
| SCHEMBL23965676 | 0.79 | ESR1 (0.41) | ESR1ESR2CYP3A4CYP2D6KMT2A | |
| SCHEMBL24983457 | 0.78 | TRPA1 (0.36) | ESR1ESR2CYP3A4CYP2D6KMT2A | |
| SCHEMBL23978107 | 0.77 | TRPA1 (0.34) | ESR1ESR2CYP3A4CYP2D6KMT2A | |
| SCHEMBL23965658 | 0.74 | TRPA1 (0.33) | ESR1ESR2CYP3A4CYP2D6KMT2A | |
| SCHEMBL23965661 | 0.73 | ESR1 (0.37) | ESR1ESR2CYP3A4CYP2D6KMT2A | |
| SCHEMBL23969498 | 0.73 | CYP3A4 (0.38) | ESR1ESR2CYP3A4CYP2D6KMT2A | |
| SCHEMBL14289796 | 0.73 | ERCC5 (0.40) | KMT2AHTTALDH1A1HPGDTSHR | |
| SCHEMBL23969512 | 0.71 | HPGD (0.45) | KMT2AMEN1TDP1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3903583-A1 | USE OF STROBILURIN TYPE COMPOUNDS FOR COMBATING PHYTOPATHOGENIC FUNGI CONTAINING AN AMINO ACID SUBSTITUTION F129L IN THE MITOCHONDRIAL CYTOCHROME B PROTEIN CONFERRING RESISTANCE TO QO INHIBITORS III | BASF SE (DE) | 2021-11-03 | — | — | EP | disclosed |